Dataset features
Specifications
Application: | Gene expression microarray analysis |
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Number of samples: | 23 |
Release date: | Mar 23 2010 |
Last update date: | Mar 22 2012 |
Access: | Public |
Chemicals: | Atrazine |
Dataset link | Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans: atrazine |
Experimental Protocol
Adults of C. elegans strain GE-31 exposed as biological replicate groups (approx 10,000) to a control and 4 concentrations of atrazine from L1 stage. Replicate populations were sampled 12 hours after the on-set of egg laying and hybridised against a common reference for purposes of normalisation.
All experiments were conducted following a reference design with the reference sample compiled from a mixture of RNA extracted from control and cadmium-, fluoranthene-, atrazine- and copper-exposed worms from L1, L4 and adult life-stages. Use of this reference was intended to provide optimal coverage of the spotted genes.
Repositories
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Peter Kille
Dataset Statistics
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Citations per year
Dataset publication
2010
BMC Syst Biol
PMCID: 2857823
PMID: 20331876
DOI: 10.1186/1752-0509-4-32