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An algorithm for the correct alignment of two nucleotide sequences containing SVs, i.e. deletion, insertion, tandem duplication or inversion. The algorithm does not require the adjustment or modification of the alignment scoring scheme(s) that is usually tuned for a particular alignment purpose, e.g. cross-species, contig or read alignments. Thus, the algorithm can be universally applied in various biological studies relying on alignment.

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AGE classification

AGE specifications

Software type:
Restrictions to use:
Academic or non-commercial use
Biological technology:
Programming languages:
Command line interface
Input format:
Operating system:
Computer skills:

AGE distribution


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Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA

Link to literature

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