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|Alternative name||Atlas of Gene Expression in Mouse Aging Project|
|Restrictions to use||None|
- Mus musculus
Publication for Atlas of Gene Expression in Mouse Aging Project
Sex‐ and tissue‐specific changes in mTOR signaling with age in C57BL/6J mice
[…] mTOR pathway as significantly affected (Zahn et al., ; Pearson et al., ).Our knowledge of the mTOR signaling pathway has significantly increased since 2007, and we therefore decided to re‐analyze the AGEMAP and Pearson et al. gene expression data from liver, muscle, and heart tissue using GSEA (gene set enrichment analysis) (Mootha et al., ; Subramanian et al., ); unfortunately, adipose gene expre […]
Novel MicroRNAs Differentially Expressed during Aging in the Mouse Brain
[…] enjamini & Hochberg method . MiRNA sequence alignment was conducted using Clustal W 2.0 , .Microarray expression profiling data of the following tissues in the brain of aging mice were retrieved from AGEMAP : cerebrum, cerebellum, hippocampus, and striatum. Mice used in AGEMAP were C57BL/6 strain; in our study, we used C57BL/6J strain mice, a subline of C57BL/6. In order to compare with our datase […]
Computational biology for ageing
[…] Gene Expression Omnibus (GEO)  allow querying and downloading of data related to functional genomics experiments, many of which have some association with ageing. For instance, data produced by the AgeMap project  that investigated gene-expression profiles from 16 mouse tissues at various time points can be retrieved from ArrayExpress and GEO. These generic resources ensure long-term access to […]
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