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ALEA | A toolbox for allele-specific epigenomics analysis

A computational toolbox for allele-specific epigenomics analysis, which incorporates allelic variation data within existing resources, allowing for the identification of significant associations between epigenetic modifications and specific allelic variants in human and mouse cells. ALEA provides a customizable pipeline of command line tools for allele-specific analysis of next-generation sequencing data (ChIP-seq, RNA-seq, etc.) that takes the raw sequencing data and produces separate allelic tracks ready to be viewed on genome browsers. The pipeline has been validated using human and hybrid mouse ChIP-seq and RNA-seq data.

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ALEA forum

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ALEA classification

ALEA specifications

Unique identifier:
OMICS_02193
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
Version:
1.2.2
Maintained:
Yes
Software type:
Toolkit/Suite
Restrictions to use:
None
Computer skills:
Advanced
Stability:
Stable

ALEA distribution

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ALEA support

Maintainer

  • Mohammad M. Karimi <>

Credits

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Publications

Institution(s)

Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada

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