AlignPI specifications

Information


Unique identifier OMICS_32940
Name AlignPI
Alternative name Align Phenome and Interactome
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability No
Maintained Yes

Maintainer


  • person_outline Rui Jiang

Publication for Align Phenome and Interactome

AlignPI citations

 (2)
library_books

A computational framework for the prioritization of disease gene candidates

2015
BMC Genomics
PMCID: 4547404
PMID: 26330267
DOI: 10.1186/1471-2164-16-S9-S2

[…] a sources and methodology. The study by Vanunu et al. [] applied a diffusion- based method named PRINCE to prioritize genes in prostate cancer, AD and type 2 diabetes. Wu et al. proposed the resource AlignPI [] which applied a network alignment approach predict disease genes. The algorithm VAVIEN [] was also developed to prioritize disease genes based on topological features of PPINs.These diverse […]

library_books

Walking on a Tissue Specific Disease Protein Complex Heterogeneous Network for the Discovery of Disease Related Protein Complexes

2013
Biomed Res Int
PMCID: 3888695
PMID: 24455720
DOI: 10.1155/2013/732650

[…] he idea of relying on phenotype similarities between diseases instead of between pre-defined seed genes to make inferences has then been extended by a series of methods, including RWRH [], PRINCE [], AlignPI [], MAXIF [], and many others [–]. In these studies, PPI networks have also been dominantly used to provide a simplified yet systematic measure of functional similarities between gene products […]

AlignPI institution(s)
MOE Key Laboratory of Bioinformatics and Bioinformatics Division, TNLIST/Department of Automation, Tsinghua University, Beijing, China
AlignPI funding source(s)
Supported by Natural Science Foundation of China (60575014 and 60805010); Hi-Tech Research and Development Program of China (863project) (2006AA02Z325); National Basic Research Program of China (2004CB518605); a startup supporting plan at Tsinghua University.

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