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Allele-specific binding software tools | ChIP sequencing data analysis

Detection of allelic imbalances in ChIP-Seq reads is a powerful approach to identify functional non-coding single nucleotide variants (SNVs), either polymorphisms or mutations, which modulate the affinity of transcription factors for…
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ALEA
Desktop

ALEA

A computational toolbox for allele-specific epigenomics analysis, which…

A computational toolbox for allele-specific epigenomics analysis, which incorporates allelic variation data within existing resources, allowing for the identification of significant associations…

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Allelome.PRO
Desktop

Allelome.PRO Allelome Profiler

A user-friendly pipeline to investigate allele specific features in…

A user-friendly pipeline to investigate allele specific features in high-throughput data using any compatible annotation and SNP file. Allelome.PRO extends approaches used in previous studies that…

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ABC
Desktop

ABC Allele-specific Binding from ChIP-Seq

A computational tool that identifies allele specific binding of transcription…

A computational tool that identifies allele specific binding of transcription factors from aligned ChIP-Seq reads at heterozygous SNVs. ABC controls for potential false positives resulting from…

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AlleleSeq
Desktop

AlleleSeq

With the evolution of DNA sequencing technology, it is now possible to study…

With the evolution of DNA sequencing technology, it is now possible to study expression and DNA binding differences between pairs of sequence alleles on the maternally- and paternally-derived…

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iASeq
Desktop

iASeq

Uses a Bayesian hierarchical mixture model to learn correlation patterns of…

Uses a Bayesian hierarchical mixture model to learn correlation patterns of allele-specificity among multiple proteins. Using the discovered correlation patterns, the model allows one to borrow…

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BaalChIP
Desktop
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