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Allele-specific binding software tools | ChIP sequencing data analysis

Allele-specific binding software tools | ChIP sequencing data analysis

Detection of allelic imbalances in ChIP-Seq reads is a powerful approach to identify functional non-coding single nucleotide variants (SNVs), either polymorphisms or mutations, which modulate the affinity of transcription factors for chromatin.

Source text:
(Bailey et al., 2015) ABC: a tool to identify SNVs causing allele-specific transcription factor binding from ChIP-Seq experiments. Bioinformatics.

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