Resources Analytics Protocols arrow_drop_down

Allele-specific copy number detection | Whole-genome sequencing data analysis

Allele-specific copy number detection | Whole-genome sequencing data analysis Estimation of allele-specific copy number (ASCN), which quantifies the number of copies of each allele at each variant loci rather than the total number of chromosome copies, is an important step in the characterization of tumor genomes and the inference of their clonal history. Sequencing produces reads containing both alleles at heterozygous variant loci, and thus, like genotyping arrays, allows the disambiguation of ASCNs. Compared to genotyping arrays, next-generation sequencing can provide finer resolution in estimating ASCNs because each person has his/her own unique heterozygous variant loci that are not included in regular genotyping arrays.
1 - 3 of 13 results
tune Filters / Sort by
Sort by:
Filter by:
build Technology
laptop Operating System
cloud_download Distribution
desktop_windows Interface
important_devices Computer Skill
copyright Restriction to use
memory Programming Language
healing Disease
import_contacts Journal
account_balance Funding
1 - 3 of 13 results

Free Trial

Claim a free trial to test our platform.