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Allelic imbalance identification software tools | Whole-exome sequencing data analysis

Whole-exome sequencing (WES) has extensively been used in cancer genome studies; however, the use of WES data in the study of loss of heterozygosity or more generally allelic imbalance (AI) has so far been very limited, which highlights the need for user-friendly and flexible software that can handle low-quality datasets.

Source text:
(Nadaf et al., 2015) ExomeAI: detection of recurrent allelic imbalance in tumors using whole-exome sequencing data. Bioinformatics.

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