Allergen databases | Immunology system data analysis

A web server that provides rapid, cross-referenced access to the sequences, structures and IgE epitopes of allergenic proteins. SDAP contains information about the allergen name, source, sequence, structure, IgE epitopes and literature references and easy links to the major protein (PDB, SWISS-PROT/TrEMBL, PIR-ALN, NCBI Taxonomy Browser) and literature (PubMed, MEDLINE) on-line servers. The computational component in SDAP uses an original algorithm based on conserved properties of amino acid side chains to identify regions of known allergens similar to user supplied peptides or selected from the SDAP database of IgE epitopes. This and other bioinformatics tools can be used to rapidly determine potential cross-reactivities between allergens and to screen novel proteins for the presence of IgE epitopes they may share with known allergens.

Aims to furnish information for the evaluation of potential allergenicity of new food proteins produced by genetically modified organisms (GMO) and novel protein ingredients in processed foods. AllergenOnline includes about 2035 sequences from 808 taxonomic-protein groups, annually updated to identify proteins that may require additional tests.

A database to collect in a single web-based resource basic and clinical information, and data about any allergenic organism and its molecular structures capable to induce an IgE-mediated disease. Allergome main goal is to collect a list of allergenic sources and molecules by using the widest selection criteria and sources. A further development of the Allergome platform has been represented by the Real Time Monitoring of IgE sensitization module (ReTiME) that allows uploading of raw data from both in vivo and in vitro testing, thus representing the first attempt to have IT applied to allergy data mining.