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AllerHunter specifications

Information


Unique identifier OMICS_08461
Name AllerHunter
Software type Package/Module
Interface Command line interface
Restrictions to use None
Input data Protein sequence
Input format FASTA
Operating system Unix/Linux
Computer skills Advanced
Stability No
Maintained No

Taxon


  • Primates
    • Homo sapiens

Versioning


No version available

Maintainer


This tool is not available anymore.

Publication for AllerHunter

AllerHunter citations

 (8)
library_books

Vaccinomics Approach for Designing Potential Peptide Vaccine by Targeting Shigella spp. Serine Protease Autotransporter Subfamily Protein SigA

2017
J Immunol Res
PMCID: 5610819
PMID: 29082265
DOI: 10.1155/2017/6412353

[…] The AllerHunter web server predicted the sequence-based allergenicity calculation very precisely. The allergenicity of the queried core epitope (IELAGTLTLT) was 0.05 (sensitivity = 98.40%, specificity = 2 […]

library_books

In silico based vaccine design against Ebola virus glycoprotein

2017
PMCID: 5367765
PMID: 28356762
DOI: 10.2147/AABC.S115859

[…] ince most vaccines convert the immune system into an “allergic” reaction by inducting Type 2 T helper cells and immunoglobulin E. That is why we predicted allergenicity of the selected epitope by the AllerHunter web server, where the probability is >0.06. The epitope HKEGAFFLY was scored 0.00 (sensitivity =91.6%, specificity =89.3%), and was thus considered a nonallergen, according to the Food and […]

library_books

Improving protein content and quality by over expressing artificially synthetic fusion proteins with high lysine and threonine constituent in rice plants

2016
Sci Rep
PMCID: 5039639
PMID: 27677708
DOI: 10.1038/srep34427

[…] motif sequences for BLAST searches against the allergy database (http://www.allergenonline.org/index.shtml). The results showed that no sequence homology was found in the database. We have also used AllerHunter (http://tiger.dbs.nus.edu.sg/AllerHunter/running.html) and Allerdictor (http://allerdictor.vbi.vt.edu/predict/) for allergen prediction of TKTKK1 and TKTKK2. No potential allergen was pred […]

library_books

A Brief Review of Computer Assisted Approaches to Rational Design of Peptide Vaccines

2016
Int J Mol Sci
PMCID: 4881492
PMID: 27153063
DOI: 10.3390/ijms17050666

[…] nine), to interact with most MHC-I alleles with high affinity. They next determined the conservancy of the B-cell epitopes from the IEDB (Immune Epitope Database) server [] and allergenicity from the AllerHunter tool and found this epitope to have 64.29% conservancy and an allergencity score well below threshold value. The next step was a molecular docking analysis, of the selected peptide with HL […]

library_books

Epitope Based Vaccine Target Screening against Highly Pathogenic MERS CoV: An In Silico Approach Applied to Emerging Infectious Diseases

2015
PLoS One
PMCID: 4671582
PMID: 26641892
DOI: 10.1371/journal.pone.0144475

[…] The allergenicity of the epitopes was analyzed by the AllerHunter server [] (http://tiger.dbs.nus.edu.sg/AllerHunter). AllerHunter is a SVM-pairwise system for assessment of allergenicity and allergic cross-reactivity in proteins. It aims to predict alle […]

library_books

Highly conserved regions in Ebola virus RNA dependent RNA polymerase may be act as a universal novel peptide vaccine target: a computational approach

2015
PMCID: 4529428
PMID: 26820892
DOI: 10.1186/s40203-015-0011-4

[…] Conservation analyses of the proposed epitopes were analyzed by the IEDB conservancy analysis tool that is shown in Table . AllerHunter server predicted the allergenicity of the queried epitope with a score was 0.03 (sensitivity =94.4. %, specificity =70.3 %). […]

Citations

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AllerHunter institution(s)
Department of Biological Sciences, National University of Singapore, Singapore, Singapore

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