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Associated diseases

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AllerTOP specifications

Information


Unique identifier OMICS_12404
Name AllerTOP
Interface Web user interface
Restrictions to use None
Input data Protein sequence
Input format Plain text (one letter code)
Computer skills Basic
Version 2.0
Stability Stable
Maintained Yes

Maintainer


  • person_outline Irini Doytchinova <>

Publications for AllerTOP

AllerTOP in publications

 (5)
PMCID: 5773588
PMID: 29348555
DOI: 10.1038/s41598-018-19456-1

[…] encountered, ordinarily harmless substance that results in sneezing, wheezing, skin rash, and swelling of the mucous membrane. allergenicity of predicted vaccine construct was determined using allertop online server and found that the vaccine protein is nonallergic in nature and safe for the human use,., the physiochemical properties of vaccine construct were characterized by using […]

PMCID: 5742776
PMID: 29207547
DOI: 10.3390/foods6120108

[…] 2), and trypsin. toxicity was scanned with default settings using toxinpred, which is available at http://www.imtech.res.in/raghava/toxinpred/multi_submit.php []. allergenicity was predicted using allertop, which is available at http://www.pharmfac.net/allertop/ [] (). , the selected peptides (ffg, ifffl, pfl, wwk, wcy, fpil, cpa, flla, fepl) were synthesised by microwave-assisted solid phase […]

PMCID: 5541426
PMID: 28768539
DOI: 10.1186/s12896-017-0384-z

[…] of allergenic potential of proteins. this hybrid approach to identify the allergenic potential was performed for all the selected chimeric cry proteins to analyse for the presence of ige epitopes., allertop (www.pharmfac.net/allertop) [] is another web based server that was used in the study for validation of the chimeric proteins. it is an alignment-free server that predicts allergenicity […]

PMCID: 4932005
PMID: 27376537
DOI: 10.1186/s40203-016-0020-y

[…] from flaa, momp, peb3, cadf proteins were capable of inducing the desired immune response as b cell epitope. among them “einkn” and “ldengce” were also found non-allergen as predicted by allertop 1.0 tool., for t cell epitope prediction, plenty of algorithms are freely available and in this study we employed iedb analysis tool which is possibly the most wide-ranging database offering […]

PMCID: 3603454
PMID: 23303307
DOI: 10.1098/rsob.120139

[…] authors thank their colleagues from the faculty of pharmacy, the medical university of sofia—ivan dimitrov, mariyana atanasova and panaiot garnev—for their contributions in the developing of epitop, allertop and epidock. i.d. thanks her former colleagues from the jenner institute, oxford university—darren r. flower, pigping guan, channa hattotuwagama and martin blythe—for their contributions […]


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AllerTOP institution(s)
Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria; Bangov Faculty of Natural Sciences, Konstantin Preslavski Shumen University, Shumen, Bulgaria; Life and Health Sciences, Aston University, Aston Triangle, Birmingham, UK
AllerTOP funding source(s)
We acknowledge the Bulgarian Science Fund for financial support (Grants DCVNP 02-1/2009 and IO1/7).

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