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Citations per year

Number of citations per year for the bioinformatics software tool AlloSigMA

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AlloSigMA specifications


Unique identifier OMICS_25247
Name AlloSigMA
Alternative name Allosteric SIGnaling and Mutation Analysis
Interface Web user interface
Restrictions to use None
Input data A protein sequence or a PDB ID.
Input format PDB
Programming languages Python
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Igor N. Berezovsky
  • person_outline Enrico Guarnera
  • person_outline Zhen Wan Tan

Publication for Allosteric SIGnaling and Mutation Analysis

AlloSigMA citation


A computational study for rational HIV 1 non nucleoside reverse transcriptase inhibitor selection and the discovery of novel allosteric pockets for inhibitor design

Biosci Rep
PMCID: 5835713
PMID: 29437904
DOI: 10.1042/BSR20171113

[…] large subunits of RT (i.e. effects caused by the pockets on the p51 subunit to the polymerase active site on the p66 subunit). For this, we used a statistical mechanical model [] (implemented in the AlloSigMA server []) to estimate the energies exerted by the allosteric communication.In the AlloSigMA server, the allosteric communications were estimated based on the responses of each residue (via […]

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AlloSigMA institution(s)
Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore; Department of Biological Sciences (DBS), National University of Singapore (NUS), Singapore

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