Alta-Cyclic specifications


Unique identifier OMICS_01149
Name Alta-Cyclic
Software type Application/Script
Interface Command line interface
Restrictions to use Academic or non-commercial use
Input format INT with Bustard reads
Biological technology Illumina
Operating system Unix/Linux
Computer skills Advanced
Version 0.2.2
Stability Stable
Maintained Yes




No version available


  • person_outline Yaniv Erlich

Publication for Alta-Cyclic

Alta-Cyclic citation


Base calling for next generation sequencing platforms

Brief Bioinform
PMCID: 3178052
PMID: 21245079
DOI: 10.1093/bib/bbq077

[…] orithm implemented in Bustard can be found in [].Within the last 2 years, numerous papers have been published which improve upon the native base-calling implementation. The first among them which was Alta-Cyclic. Alta-Cyclic uses a parametric model for dephasing and then corrects for cross-talk using a cycle dependent cross-talk matrix. Support Vector Machines (SVM) are used to determine the base […]

Alta-Cyclic institution(s)
Watson School of Biological Sciences, Cold Spring Harbor, NY, USA; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
Alta-Cyclic funding source(s)
Supported by grants from the US National Institute of Health, the National Science Foundation and the Stanley Foundation.

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