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Alternative splicing annotation software tools | RNA modification data analysis

Alternative splicing annotation software tools | RNA modification data analysis

The alternative splicing of messenger RNA generates a range of mature RNA transcripts, which if translated into stable proteins, would greatly enrich the repertoire of cellular functions (Smith and Valcarcel, 2000; Tress et al., 2007). The functional annotation of these alternative isoforms presents a serious challenge, not least because of the sheer quantity of genomic data that is being generated by genome annotation projects (Mudge et al., 2011; Frankish et al., 2012). Source text: Rodriguez et al., 2015.

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