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Alternative splicing identification software tools | Single-cell RNA sequencing data analysis

Single cell RNA-seq experiments provide valuable insight into cellular heterogeneity but suffer from low coverage, 3' bias and technical noise. These unique properties of single cell RNA-seq data make study of alternative splicing difficult, and…
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AltAnalyze
Desktop

AltAnalyze

An easy-to-use application for microarray, RNA-Seq and metabolomics analysis.…

An easy-to-use application for microarray, RNA-Seq and metabolomics analysis. For splicing sensitive platforms (RNA-Seq or Affymetrix Exon, Gene and Junction arrays), AltAnalyze will assess…

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SingleSplice
Desktop

SingleSplice

A tool for studying alternative splicing using single cell RNA-seq data.…

A tool for studying alternative splicing using single cell RNA-seq data. SingleSplice uses a statistical model to detect genes whose isoform usage varies more than expected from the effects of…

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BRIE
Desktop

BRIE Bayesian Regression for Isoform Estimation

Quantifies splicing in individual single cells. BRIE is a flexible framework…

Quantifies splicing in individual single cells. BRIE is a flexible framework that detects differential splicing between individual cells from scRNA-seq data. This method was developed for modelling…

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ISOP
Desktop

ISOP ISOform-Patterns

A method for analysis and characterization of single-cell isoform-level gene…

A method for analysis and characterization of single-cell isoform-level gene expression data. ISOP enables analysis of single-cell preference, commitment and heterogeneity of isoform level…

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outrigger
Desktop

outrigger

Uses junction reads from RNA seq data, and a graph database to create a de novo…

Uses junction reads from RNA seq data, and a graph database to create a de novo alternative splicing annotation with a graph database. Outrigger is a Python package and an RNA-seq analysis software…

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