Offers a sequence screening service allowing users to screen sequences of interest for matching fragments with validated amyloidogenic regions. AmyPro provides comprehensive information on the entry sequences, including (i) precursor proteins, (ii) experimentally validated amyloidogenic sequence regions, (iii) short description of the functional relevance of their soluble and amyloid states, and (iv) list of the experimental techniques used to discover and investigate the amyloid state.
Protein Data Bank in Europe, European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK; MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, UK; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Brussels, Belgium; Interuniversity Institute of Bioinformatics in Brussels (IB)2, ULB-VUB, Brussels, Belgium; VIB Center for Structural Biology, Vrije Universiteit Brussel (VUB), Brussels, Belgium; Institute of Enzymology, Research Centre for Natural Sciences of the HAS, Budapest, Hungary
AmyPro funding source(s)
Supported by European Molecular Biology Organization Fellowship [ALTF 702-2015]; European Commission Marie Sk-lodowska-Curie Fellowship [H2020-MSCAIF-2014 ST–653963]; Research FoundationFlanders (FWO) project [FWOAL796]; FWO Odysseus G.0029.12 and OTKA (Hungarian Scientific Research Grant) [ANN 111056].