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Analysis of DNA methylation in genomic regions ADMIRE

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Allows to analyze and visualize differential methylation in genomic regions. ADMIRE is a semi-automatic pipeline that features five different normalization methods and performs two one-sided two-sample rank tests (Mann–Whitney U tests). The software features arbitrary experimental settings, quality control, automatic filtering, normalization, multiple testing, differential analyses on arbitrary genomic regions. It additionally implements a gene set enrichment procedure.

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ADMIRE versioning

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ADMIRE classification

ADMIRE specifications

Software type:
Pipeline/Workflow
Restrictions to use:
None
Output data:
Tables and graphs
Operating system:
Unix/Linux
License:
MIT License
Version:
1.0
Requirements:
comb-p, bedtools, Rscript, numpy, matplotlib
Maintained:
Yes
Interface:
Command line interface
Input data:
Infinium Human Methylation450K Assay
Biological technology:
Illumina
Programming languages:
Perl, Python, R, Shell (Bash)
Computer skills:
Advanced
Stability:
Stable

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ADMIRE forum

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Participate in the forum to get support for using tools. Ask questions about technical specifications.

No open topic.

ADMIRE classification

ADMIRE specifications

Interface:
Web user interface
Input data:
Infinium Human Methylation450K Assay
Biological technology:
Illumina
Computer skills:
Basic
Stability:
Stable
Restrictions to use:
None
Output data:
Tables and graphs
Programming languages:
Perl, R
Version:
1.0
Maintained:
Yes

ADMIRE support

Maintainers

  • Mario Looso <>
  • Jens Preussner <>
  • Mario Looso <>
  • Jens Preussner <>

Additional information

http://admire.readthedocs.io/en/latest/

Credits

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Publications

Institution(s)

Bioinformatics Group, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

Funding source(s)

Supported by Excellence Cluster Cardio-Pulmonary System (ECCPS) and Max Planck Institute for Heart and Lung Research (MPI).

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