Ancestral sequence reconstruction (ASR) methods require as input both a multiple sequence alignment (MSA) of existing sequences and a corresponding phylogenetic tree (either provided or computed from the MSA). They output a statistical inference of the ancestral sequence at any…
Desktop app
Cocos Cocos

Cocos

Constructs phylogenies of multi-domain proteins. With a given species tree and…

Constructs phylogenies of multi-domain proteins. With a given species tree and domain phylogenies, the procedure infers the composition of ancestral multi-domain proteins. Cocos implements and extend…

Desktop app
Web app
FastML FastML

FastML

A user-friendly tool for the reconstruction of ancestral sequences. FastML…

A user-friendly tool for the reconstruction of ancestral sequences. FastML implements various novel features that differentiate it from existing tools: (i) FastML uses an indel-coding method, in…

Desktop app
Web app
maxAlike maxAlike

maxAlike

Reconstructs a genomic sequence for a specific taxon based on sequence homologs…

Reconstructs a genomic sequence for a specific taxon based on sequence homologs in other species. The input is a multiple sequence alignment and a phylogenetic tree that also contains the target…

Web app
Ancestors Deprecated Ancestors

Ancestors

A web server allowing one to easily and quickly perform the last three steps of…

A web server allowing one to easily and quickly perform the last three steps of the ancestral genome reconstruction procedure. Ancestors implements several alignment algorithms, an indel maximum…

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