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AnEnPi specifications


Unique identifier OMICS_22396
Name AnEnPi
Alternative name Analogous Enzyme Pipeline
Interface Web user interface
Restrictions to use Academic or non-commercial use
Programming languages Perl
Computer skills Basic
Stability No
Maintained No


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Publication for Analogous Enzyme Pipeline

AnEnPi in publications

PMCID: 5470852
PMID: 28638238
DOI: 10.1177/1177932217712471

[…] of enzymatic functionality, secondary and tertiary protein structures, protein domain architecture, and metabolic environment. from 67 enzymes represented by 42 enzymatic activities classified by anenpi (analogous enzymes pipeline) as specific for l major compared with h sapiens, only 40 (23 enzyme commission [ec] numbers) could actually be considered as strictly specific of l major and 27 […]

PMCID: 4182287
PMID: 25336895
DOI: 10.4137/EBO.S13759

[…] proteins. then, the protein primary structures inside each protein functional group were compared in a pairwise, all-against-all manner, using blastp. functional activities were confirmed via the anenpi’s module, which classifies the enzymes in accordance to the ec number. this classification is obtained after parsing the results of blastp, using the data set of predicted proteins from l. […]

PMCID: 4007602
PMID: 23497072
DOI: 10.1186/1471-2164-14-149

[…] state of the parasite (additional file : table s2)., functional annotation of rna derived contigs was carried out using a set of complementary tools: estscan [], blast2go [], interproscan [] and anenpi []. in the first place, to identify t. vivax genes encoding proteins with a known or unknown function, it was necessary to obtain high quality virtual translation of contigs. this translation […]

PMCID: 3145330
PMID: 21808726
DOI: 10.4061/2011/543912

[…] thus allowing the development of molecules against one or other isoform. from public data of the tritryps' genomes, we reconstructed the genetic information processing pathways (gipps). we then used anenpi to look for the presence of these enzymes between homo sapiens and tritryps, as well as specific enzymes of the parasites. we identified three candidates (ecs and 6.1.1.-) […]

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AnEnPi institution(s)
Laboratory for Functional Genomics and Bioinformatics, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil; Ataulpho de Paiva Foundation, Rio de Janeiro, Brazil
AnEnPi funding source(s)
Supported by CNPq, CAPES, FAPERJ, the World Community Grid, the Bioinformatics Platform PDTIS/Fiocruz and Fiocruz/PAPES.

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