A sophisticated information system dedicated to the biology of ascidians, and which consists of two classes of inter-linked databases. The Developmental Browser formalizes, integrates and displays an extensive set of complementary and inter-related molecular and anatomical data for each species, which can be explored via four main menus giving access to functional annotations of genes and cis-regulatory sequences, to descriptions of anatomical entities, to gene expression data and to literature articles. Dedicated Genome Browsers complement this information by providing a visualization of genetic elements in their chromosomal context. One of the originalities of the system is to go beyond the classical hierarchical textual representation of anatomical entities found in most model organism databases and to provide a description of the shapes, neighborhood and area of cell contacts up to the early gastrula stage.
Centre de Recherches de Biochimie Macromoléculaire (CRBM), UMR5237, CNRS-Université de Montpellier, Montpellier, France; Institut de Biologie du Développement de Marseille (IBDM), UMR7288 CNRS-Aix Marseille Université, Parc Scientifique de Luminy, Marseille, France
ANISEED funding source(s)
Fondation pour la Recherche Médicale (FRM) [ING20121226356, ING20100118205]; Agence Nationale de la Recherche (ANR) [TED, ANR-13-BSV2-0011-01]; Centre National de la Recherche Scientifique [PIME grant]; NIH/NIGMS GM100466, NIH/NIGMS grant R01GM096032 and NIH/NHLBI grant R01HL108643; a Long Term EMBO fellowship; subcontract from the TEFOR infrastructure