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Angiogenesis is the process of formation of new blood vessels to make a supply of nutrients and a waste disposal pathway. This physiological process is a vital event in cancer progression-transition tumors from a benign state to a malignant one- and spread of a tumor (metastasis). Nowdays, decreasing or inhibiting angiogenesis is a new area in cancer therapy and is in the center of other angiogenesis-dependent disease therapy. Recognition the anti-angiogenic peptides has stimulated great interest among researchers in the cancer treatment field during recent years.
(Zahiri et al., 2017) AntAngioCOOL: An R Package for Computational Detection of Anti-Angiogenic Peptides. bioRxiv.