Main logo
?
tutorial arrow
×
Submit new tools
Share tools covering the current topic. Provide easy-to-follow guidelines to improve their usability.
Share new tools with the community
Sign up for free to promote the availability of bioinformatics tools

Antibody modeling software tools | Immunoinformatics

Computational modeling of antibody structure is a crucial step in engineering new antibody molecules, but there are few tools available to the general public, and accurately modeling loops in complementary determining regions (CDRs) remains an open…
ABGEN
Desktop

ABGEN AntiBody structure GENeration

Obtains structural models of antibody fragments. ABGEN utilizes a homology…

Obtains structural models of antibody fragments. ABGEN utilizes a homology based scaffolding technique, and includes the use of invariant and strictly conserved residue replacements and key…

ABodyBuilder
Web

ABodyBuilder

An antibody modeling pipeline that uses SAbDab knowledge-base of antibody…

An antibody modeling pipeline that uses SAbDab knowledge-base of antibody structures to guide decision-making in modeling antibodies. ABodyBuilder can rapidly build accurate models of antibodies from…

SAbPred
Web

SAbPred

A web server to make structure-based predictions for antibody engineering and…

A web server to make structure-based predictions for antibody engineering and design. It can be used to annotate the sequences of antibodies with different numbering schemes, automatically produce…

LYRA
Web

LYRA LYmphocyte Receptor Automated modeling

Implements a complete and automated method for building of B- and T-cell…

Implements a complete and automated method for building of B- and T-cell receptor structural models starting from their amino acid sequence alone. LYRA is based on the canonical structure method and…

ANARCI
Web
Desktop

ANARCI Antigen receptor Numbering And Receptor ClassificatIon

A tool for annotating antigen receptor variable domain amino-acid sequences…

A tool for annotating antigen receptor variable domain amino-acid sequences with five commonly used numbering schemes. It can annotate sequences with the five most popular numbering schemes: Kabat,…

Parapred
Desktop

Parapred

Leverage features from local residue neighbourhoods and across the entire…

Leverage features from local residue neighbourhoods and across the entire sequence using deep-learning architecture. Parapred provides a method for sequence-based prediction of paratope residues. It…

PIGSPro
Web

PIGSPro Prediction of Immunoglobulin Structure Pro

Builds the structure of immunoglobulins based on the canonical structure model…

Builds the structure of immunoglobulins based on the canonical structure model and subsequent modifications. PIGSPro is a web server that includes the option of selecting the two frameworks from the…

RosettaAntibody
Web

RosettaAntibody

Predicts the structure of an antibody variable region given the amino-acid…

Predicts the structure of an antibody variable region given the amino-acid sequences of the respective light and heavy chains. In an initial stage, RosettaAntibody identifies and displays the most…

IGPred
Web

IGPred

A sequence-based tool for identifying immunoglobulins. We designed a predictor…

A sequence-based tool for identifying immunoglobulins. We designed a predictor by formulating protein sequences with the pseudo amino acid composition into which nine physiochemical properties of…

H3Loopred
Desktop

H3Loopred

A method, based on the Random Forest automatic learning technique, to select…

A method, based on the Random Forest automatic learning technique, to select structural templates for H3 loops among a dataset of candidates. These can be used to predict the structure of the loop…

Kotai Antibody…
Web

Kotai Antibody Builder

A web app for tertiary structural modeling of antibody variable regions. Kotai…

A web app for tertiary structural modeling of antibody variable regions. Kotai Antibody Builder constructs three-dimensional (3D) structures of antibody variable domains from sequence using canonical…

PIGS
Web

PIGS

A web server for the automatic modeling of immunoglobulin variable domains…

A web server for the automatic modeling of immunoglobulin variable domains based on the canonical structure method. PIGS has a user-friendly and flexible interface, that allows the user to choose…

SmrtMolAntibody
Web

SmrtMolAntibody

Takes an input antibody sequence and returns an energy optimized accurate…

Takes an input antibody sequence and returns an energy optimized accurate structure in minutes. SmrtMolAntibody is part of a suite of modeling tools provided by Macromoltek. It creates a structure of…

FREAD
Web

FREAD

A database search loop modelling algorithm. Its primary use is to fill in the…

A database search loop modelling algorithm. Its primary use is to fill in the gaps in incomplete 3D models of protein structures. The input is a 3D model of a protein structure as well as the…

OptCDR
Desktop

OptCDR

Is used in the de novo design of antibody binding pockets against specified…

Is used in the de novo design of antibody binding pockets against specified antigen epitopes. OptCDR proposes a four-step procedure. First, canonical structures are selected for the six…

ABangle
Desktop
Web

ABangle

The binding site of an antibody is formed between the two variable domains, VH…

The binding site of an antibody is formed between the two variable domains, VH and VL, of its antigen binding fragment (Fab). ABangle allows the VH-VL orientation for any antibody to be automatically…

Scaligner
Web

Scaligner

Analyzes antibody sequences. Scaligner allows users to store sequences in a…

Analyzes antibody sequences. Scaligner allows users to store sequences in a secure repository, identifies Complementary Determining Region (CDR) and numbers amino acids using Kabat and IMGT schemes.…

DNAPLOT
Web

DNAPLOT

Provides a base for systematic analyses of expressed immune repertoires.…

Provides a base for systematic analyses of expressed immune repertoires. DNAPLOT helps to detect patterns of changes in the complementary determining region (CDR) regions of a given repertoire. It…

abYsis
Dataset

abYsis

Allows exploration of antibody sequence and structure. abYsis accepts users’…

Allows exploration of antibody sequence and structure. abYsis accepts users’ sequence data. It offers a way to pair light and heavy chain sequences. This database gathers antibody protein sequences…

WAM
Desktop

WAM Web Antibody Modelling

Offers an improved algorithm for complementarity determining region (CDR)-H3…

Offers an improved algorithm for complementarity determining region (CDR)-H3 modelling. WAM has been launched as an online modelling service. It constructs 3D models of antibody variable region…

Information

By using OMICtools you acknowledge that you have read and accepted the terms of the end user license agreement.