Antigen databases | Immunology system data analysis
Human and animal health is threatened by various diseases every day. Acquired as a result of pathogenic microbial agents, infectious diseases are still a major source of mortality throughout the world, contributing to 26% of global mortality in 2001. Of these mortalities, 90% are caused by illnesses such as acute respiratory infections, diarrheal diseases, malaria, AIDS, tuberculosis and measles. Cancer, allergy and many other diseases also cause significant mortality and morbidity in human and animal victims.
Generates protein affinity reagents to a large number of human transcription factors. PCRP consists of three core centers: antigen production, traditional monoclonal antibody (mAb) production, and recombinant phage displayed antibody binding fragment (rAb) production. It has produced a combined total of over 1,500 rAbs and mAbs. The database was designed to establish and test high-throughput methods which offers the advantages of comprehensiveness, uniform protocols and reduced cost.
A database that combines antigenic data of flaviviruses, specialized analysis tools, and workflows for automated complex analyses focusing on applications in immunology and vaccinology. FLAVIdB represents a new generation of databases in which data and tools are integrated into a data mining infrastructures specifically designed to aid rational vaccine design by discovery of vaccine targets.
A manually curated hapten database integrating information from literature and web resources. The haptens are classified regarding their origin: pesticides, herbicides, insecticides, drugs, natural compounds, etc. Queries allow identification of haptens and associated antibodies according to functional class, carrier protein, chemical scaffold, composition or structural similarity.
Provides information about the mimicry proteins and peptides of both host (and model) and pathogen. miPepBase is a resource that includes the names of host and pathogen proteins, sequences of mimicry peptide, autoimmune disease caused due to mimicry peptide, gene ontology information of the protein, PDB ID of the structure of protein, or type of immunological response generated by mimicry peptide.
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