In the battle against viruses, antiviral peptides (AVPs) had demonstrated the immense potential. Presently, more than 15 peptide-based drugs are in various stages of clinical trials. Emerging and re-emerging viruses further emphasize the efforts to accelerate antiviral drug discovery efforts.
Furnishes a library dealing with annotated HTLV-1 proviral sequences derived from clinical, epidemiological and geographical studies publicly available. The HTLV-1 database contains more than 2000 annotated sequences. Searches can be made by specific search fields, as well as genomic region, subtype, subgroup, geographic region of origin, and continent of origin, to allow various data combinations.
Contains presumably all compounds for which the antiviral activity or viral protein binding was measured at least once. ViralDB stores antiviral activity data from ChEMBL obtained via a semi-automatic procedure extraction. These data were annotated by virus taxa according to International Committee for Taxonomy of Viruses (ICTV) taxonomy, and compound structures and activity values were standardized to obtain antiviral activity profile for each compound.
A manually curated database of experimentally verified HIV inhibiting peptides targeting various steps or proteins involved in the life cycle of HIV e.g. fusion, integration, reverse transcription etc.