A database of vertebrate polyadenylation (PA) sites determined by 3' end sequencing, using massive analysis of complementary DNA ends. APADB provides (A)PA sites for coding and non-coding transcripts of human, mouse and chicken genes. For human and mouse, several tissue types, including different cancer specimens, are available. APADB records the loss of predicted miRNA binding sites and visualizes next-generation sequencing reads that support each PA site in a genome browser.
Plant Molecular Biology, Molecular BioSciences, University of Frankfurt am Main, Frankfurt, Germany; GenXPro GmbH, Frankfurt Innovation Center Biotechnology, Frankfurt, Germany; Molecular Bioinformatics Group, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt, Germany