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APD specifications


Unique identifier OMICS_05706
Name APD
Alternative name Antimicrobial Peptide Database
Restrictions to use None
Data access File download, Browse
Version 3.0
Maintained Yes

Publications for Antimicrobial Peptide Database

APD citations


Large scale mapping of bioactive peptides in structural and sequence space

PLoS One
PMCID: 5774755
PMID: 29351315
DOI: 10.1371/journal.pone.0191063

[…] ent of chronic disease []. In this sense, several databases and bioinformatics tools have been developed to predict and study BP occurrence in food proteins. Among the databases, we found PepBank [], Antimicrobial Peptide Database (APD) [] and BIOPEP []. Databases are the main source of information to predict occurrence of BP in proteins. Basically, primary structure information of characterized p […]


Selection strategy of phage displayed immunogens based on an in vitro evaluation of the Th1 response of PBMCs and their potential use as a vaccine against Leishmania infantum infection

PMCID: 5740923
PMID: 29268793
DOI: 10.1186/s13071-017-2576-8

[…] ical properties of B1 and D11 phage-exposed peptides, such as molecular weight, hydrophobicity, and net charge were predicted, using the Compute pI/Mw tool (http://web.expasy.org/compute.pi/) and the antimicrobial peptide database server (http://aps.unmc.edu/AP/prediction/prediction main.php). […]


The rumen microbiome: an underexplored resource for novel antimicrobial discovery

PMCID: 5711939
PMID: 29214045
DOI: 10.1038/s41522-017-0042-1

[…] Prediction of AMP sequences within the identified ORFs was achieved using a variety of software available at various public databases. Specifically, we used the antimicrobial peptide database, the Antimicrobial Sequence Scanning System (AMPA), BACTIBASE, collection of anti-microbial peptides (CAMP),, and antibacterial peptides (AntiBP). Only ORFs that were pr […]


Multi label Learning for Predicting the Activities of Antimicrobial Peptides

Sci Rep
PMCID: 5438384
PMID: 28526820
DOI: 10.1038/s41598-017-01986-9

[…] were considered and no existing multi-label learning methods were tested. To address these problems, firstly we constructed a new dataset with twelve biological activities covered based on the latest antimicrobial peptide database (APD) and a filtered dataset with only five activities covered but more biological significance; secondly, several previously described multi-label learning methods and […]


New Disulfide Stabilized Fold Provides Sea Anemone Peptide to Exhibit Both Antimicrobial and TRPA1 Potentiating Properties

PMCID: 5450702
PMID: 28468269
DOI: 10.3390/toxins9050154
call_split See protocol

[…] The BLAST search engine [], the Antimicrobial Peptide Database [], the InterProScan tool [] and StellaBase [] was used to search for homologues sequences. The SignalP4.1 server [] was used to predict the potential cleavage site of t […]


High Specific Selectivity and Membrane Active Mechanism of Synthetic Cationic Hybrid Antimicrobial Peptides Based on the Peptide FV7

Int J Mol Sci
PMCID: 5343874
PMID: 28178190
DOI: 10.3390/ijms18020339
call_split See protocol

[…] The primary peptide physicochemical parameters and sequences were calculated using bioinformatics programs including ProtParam (ExPASy Proteomics Server) [] and the antimicrobial peptide database []. The secondary structure type of each residue was predicted online using Jpred 3 [] and I-TASSER []. […]


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APD institution(s)
Department of Pathology and Microbiology, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE, USA
APD funding source(s)
NIH grant R01AI105147

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