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APPRIS | Annotation of principal and alternative splice isoforms


The main goal of developing the APPRIS WebServer and WebServices is to allow users to annotate splice isoforms and select a principal isoform for vertebrate genome species beyond those that are annotated in the APPRIS Database, to annotate genes and variants that are missing from the APPRIS Database, and to annotate their experimental results with existing annotations. The APPRIS WebServer has been designed to be used for the comparison of splice isoform annotations for individual genes, while the APPRIS WebServices have been created to allow access to the APPRIS Database and to run an automatic version of the APPRIS server, using REST architecture to be portable, modular and flexible in the automation of programmatic scripts.

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APPRIS classification

  • Animals
    • Danio rerio
    • Homo sapiens
    • Mus musculus
    • Rattus norvegicus

APPRIS specifications

Unique identifier:
Restrictions to use:
Web user interface
Computer skills:


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Spanish National Bioinformatics Institute (INB) and Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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