APPRIS specifications


Unique identifier OMICS_01881
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus
    • Rattus norvegicus
  • Vertebrates
    • Danio rerio

Publications for APPRIS

APPRIS in publications

PMCID: 5865188
PMID: 29572503
DOI: 10.1038/s41467-018-03667-1

[…] point, we employed additional filters to exclude cases where exon–intron structures of conserved genes have changed in evolution. first, we considered all principal or alternative isoforms from the appris database, which provides those isoforms of a given gene that exhibit the highest cross-species conservation and the most conserved protein features. for each query species, we then considered […]

PMCID: 5778607
PMID: 29202200
DOI: 10.1093/nar/gkx1165

[…] that are used in a tissue-dependent manner and that result in tdu., next, we asked which regions of genes were subject to tissue-dependent exon usage. we integrated information from the ensembl and appris databases to annotate each exonic region. importantly, appris uses information about protein structures, functional data, selective pressure analyses and cross-species conservation to infer […]

PMCID: 5511795
PMID: 28717660
DOI: 10.1002/mgg3.291

[…] all the genbank refseq transcripts used by hgmd for that gene (hgmd transcripts). additionally, for those genes of the somatic subpanel, variants were also annotated according to the most prioritary appris transcript listed by ensembl, unless this coincided with an hgmd transcript. the refseq transcript genbank accession numbers were: abl1 nm_007313.2; akt1 nm_005163.2; alk nm_004304.4; apc […]

PMCID: 5155386
PMID: 27964752
DOI: 10.1186/s13059-016-1090-1

[…] finally, in order to organize, store, and facilitate the access to the entire set of annotations we have developed a mysql ( relational database. the modules implemented in appris ( were used to map a range of conserved protein features to the splice variants annotated for each gene and to determine […]

PMCID: 4946291
PMID: 27441289
DOI: 10.1016/j.heliyon.2016.e00065

[…] says that the existence of different specific objects and their features is not a property of the world per se, but is characteristic of a particularly human vision of the outside world: ‘nous avons appris à classer ces sensations, en qualifiant tel son d’aigu ou de grave, telle couleur de bleu ou de jaune. les couleurs – le ‘bleu’, le ‘rouge’ - ou les sons – le ‘la’, le ‘do’ - ne sont donc […]

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APPRIS institution(s)
Spanish National Bioinformatics Institute (INB) and Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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