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A tool that allows multi-locus and multi-level association analysis of genotypic and phenotypic data. APSampler was tested on a simulated data set and on a case-control MS (multiple sclerosis) study for ethnic Russians. For the simulated data, the algorithm identified all the phenotype-associated allele combinations coded into the data and, for the MS data, it replicated the previously known findings.

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APSampler classification

APSampler specifications

Software type:
Package
Restrictions to use:
None
Programming languages:
C, C++, Perl
Computer skills:
Advanced
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
MIT License
Stability:
Stable

Credits

Publications

  • (Favorov et al., 2005) A Markov chain Monte Carlo technique for identification of combinations of allelic variants underlying complex diseases in humans. Genetics.
    PMID: 16118183

Link to literature

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