Provides structured and detailed information about the experimental conditions under which aptamers were selected and their binding affinity quantified. Aptamer Base is an open collaborative database with a unique resource that can be updated and curated in a decentralized manner, thereby accommodating the ever evolving filed of aptamer research. Aptamer Base describes the pH, temperature, salt concentrations and the buffering agent for all systematic evolution of ligands by exponential enrichment (SELEX) experiments.
Department of Biology, Carleton University; Department of Chemistry, Carleton University; Institute of Biochemistry, Department of Biology and Department Chemistry, Carleton University; School of Computer Science, Carleton University, Ottawa, ON, Canada
Aptamer Base funding source(s)
This work was supported by the Natural Sciences and Engineering Research Council Discovery Grants.