ARIEL statistics

To access cutting-edge analytics on consensus tools, life science contexts and associated fields, you will need to subscribe to our premium service.

Subscribe
info

Citations per year

Citations chart
info

Popular tool citations

chevron_left Rare variant association chevron_right
Popular tools chart
info

Tool usage distribution map

Tool usage distribution map
info

Associated diseases

Associated diseases

ARIEL specifications

Information


Unique identifier OMICS_24939
Name ARIEL
Alternative name Accumulation of Rare variants Integrated and Extended Locus-specific test
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes

Versioning


Add your version

Maintainers


  • person_outline Eleftheria Zeggini <>
  • person_outline Jennifer Asimit <>

Publication for Accumulation of Rare variants Integrated and Extended Locus-specific test

ARIEL in publications

 (3)
PMCID: 5408830
PMID: 28449691
DOI: 10.1186/s13059-017-1212-4

[…] information across multiple rare variants within a specific genomic functional unit (e.g. gene, exon). rare variant region-based methods can be grouped in four broad categories (tableĀ ).table 1 ariel accumulation of rare variants integrated and extended locus-specific, asum data-adaptive sum test, cast cohort allelic sums test, cmc combined multivariate and collapsing, ec exponential […]

PMCID: 4895384
PMID: 26866487
DOI: 10.1186/s12863-015-0316-7

[…] and range from a simple indicator of whether a genetic region contains at least 1 rare variant (eg, cast [cohort allelic sums test] []), to a sum of the rare variants within a region (eg, ariel [accumulation of rare variants integrated and extended locus-specific test] [], cmc [combined multivariate and collapsing] [], and mz [morris and zeggini] []), to a weighted sum of the rare variants […]

PMCID: 4593572
PMID: 26436424
DOI: 10.1371/journal.pone.0139355

[…] sums test (cast) [], combined multivariate and collapsing (cmc) [], weighted sum (w-sum) test of madsen and browning [], kernel based adaptive cluster (kbac) [], replication based test (rbt) [], ariel test [], and erec test []; (2) methods based on model selection such as seq-asum and seq-asum-vs approaches [, ], variable threshold test (vt) [], rarecover method [], selective grouping method […]


To access a full list of publications, you will need to upgrade to our premium service.

ARIEL institution(s)
Wellcome Trust Sanger Institute, Hinxton, UK; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
ARIEL funding source(s)
Supported by the Wellcome Trust (098051).

ARIEL reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review ARIEL