Conducts simulations of models of bacteria, antibiotics, enzymes, and their interactions. ARSim leans on four models that constitute the processes of antibiotic resistance, bacteria-antibiotic interactions, enzymes, and the environment. It integrates horizontal and vertical transfer mechanisms of antibiotic resistance genes. This tool is useful for the discovery or the development of new antibiotics.
Laboratory of Computational Biology & Bioinformatics, Institute of Public Health and Environment, Graduate School of Public Health, Seoul National University, Seoul, Korea; Interdisciplinary Graduate Program in Bioinformatics, College of Natural Science, Seoul National University, Seoul, Korea
ARSim funding source(s)
Supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2016R1C1B2015511) and the Ministry of Education (No. 2017R1D1A1B03033413).