A collection of databases dedicated to the arthropod metabolism reconstruction. ArthropodaCyc allows researchers to perform reliable metabolism comparisons of fully sequenced arthropods genomes. Since the annotation quality is a key factor when performing such global genome comparisons, all proteins from the genomes included in the ArthropodaCyc database were re-annotated using several annotation tools and orthology information. All functional/domain annotation results and their sources were integrated in the databases for user access. Currently, ArthropodaCyc offers a centralized repository of metabolic pathways, protein sequence domains, Gene Ontology annotations as well as evolutionary information for 28 arthropod species. Such database collection allows metabolism analysis both with integrated tools and through extraction of data in formats suitable for systems biology studies.
Univ Lyon, INSA-Lyon, INRA, BF2I, Villeurbanne, France; Centre for Genomic Regulation, the Barcelona Institute of Science and Technology, Barcelona, Spain; Univ Lyon, Univ Lyon, CNRS, LBBE, UMR5558, Villeurbanne, France; Universitat Pompeu Fabra, Barcelona, Spain; Institucio Catalana de Recerca i Estudis Avanc¸ats, Barcelona, Spain
ArthropodaCyc funding source(s)
The ANR Blanc Program IMetSym (ANR-13-BSV7-0016-03), the Spanish Ministry of Economy and Competitiveness grants, ‘Centro de Excelencia Severo Ochoa 2013-2017’ SEV-2012-0208 and BIO2012-37161 cofounded by European Regional Development Fund