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ASLtbx specifications


Unique identifier OMICS_30749
Name ASLtbx
Alternative name Arterial Spin Labeled Perfusion MRI data processing toolbox
Software type Package/Module, Toolkit/Suite
Interface Graphical user interface
Restrictions to use Academic or non-commercial use
Input format NIFTI
Operating system Unix/Linux
Programming languages MATLAB
License GNU General Public License version 3.0
Computer skills Medium
Stability Stable
Registration required Yes
Maintained Yes


No version available



  • person_outline Ze Wang

Publications for Arterial Spin Labeled Perfusion MRI data processing toolbox

ASLtbx citations


Phosphodiesterase‐5 inhibition potentiates cerebrovascular reactivity in chronic traumatic brain injury

PMCID: 5899908
PMID: 29687019
DOI: 10.1002/acn3.541

[…] re‐sliced to correct for head motion. They were smoothed using an isotropic Gaussian kernel with a 4 mm full‐width at half‐maximum. CBF images were reconstructed using the ASL Data Processing Toolbox ASLtbx. […]


Caffeine Caused a Widespread Increase of Resting Brain Entropy

Sci Rep
PMCID: 5807546
PMID: 29426918
DOI: 10.1038/s41598-018-21008-6

[…] (MNI) space using the nonlinear transform obtained by registering the structural MR image into the MNI space using SPM12.ASL CBF images were processed using the SPM12 based batch scripts provided in ASLtbx. The following steps were included: (1) the origins of structural image, M0 map, and ASL images were set to be the center of the image matrix; (2) ASL CBF maps were calculated from the delta M […]


Patient Specific Alterations in CO2 Cerebrovascular Responsiveness in Acute and Sub Acute Sports Related Concussion

PMCID: 5787575
PMID: 29416525
DOI: 10.3389/fneur.2018.00023
call_split See protocol

[…] l CVR analyses were not blinded since they were based on the results of the first-level analysis.An ASL toolbox was used to undertake preprocessing of the pCASL data ( […]


Altered perfusion of the sensorimotor cortex in patients with cervical spondylotic myelopathy: an arterial spin labeling study

PMCID: 5769569
PMID: 29391824
DOI: 10.2147/JPR.S148076

[…] The pCASL and high-resolution T1WI data were processed using the ASLtbx toolbox ( in MATLAB (Math Works, Natick, MA, USA). Data processing was implemented as follows: 1) per-processing: median filter (nonlinear digital filtering […]


Aberrant perfusion and its connectivity within default mode network of first episode drug naïve schizophrenia patients and their unaffected first degree relatives

Sci Rep
PMCID: 5700958
PMID: 29170485
DOI: 10.1038/s41598-017-14343-7

[…] As we performed recently, data analysis was implemented in Arterial Spin Labeling Perfusion MRI Signal Processing Toolbox (ASLtbx; in accordance with reports by Wang et al.–. The detailed procedures, partly based on SPM12 (, included image reorient […]


Post conventional moral reasoning is associated with increased ventral striatal activity at rest and during task

Sci Rep
PMCID: 5541100
PMID: 28769072
DOI: 10.1038/s41598-017-07115-w

[…] Data analysis was performed using SPM8 ( and ASL Data Processing Toolbox, ASLtbx ( For each subject, functional images were realigned to correct for head motion and coregistered with the anatomical image. Perfusion weighted imag […]


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ASLtbx institution(s)
Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, PA, USA

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