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ATIVS specifications


Unique identifier OMICS_23553
Alternative name Analysis Tools for Influenza virus surveillance
Interface Web user interface
Restrictions to use None
Input format XLS,FASTA
Output data An antigenic map.
Programming languages Java
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Chao Hsiung
  • person_outline Min-Shi Lee

Publication for Analysis Tools for Influenza virus surveillance

ATIVS citations


MF59 adjuvanted influenza vaccine (FLUAD®) elicits higher immune responses than a non adjuvanted influenza vaccine (Fluzone®): A randomized, multicenter, Phase III pediatric trial in Mexico

PMCID: 5806633
PMID: 28925801
DOI: 10.1080/21645515.2017.1373227

[…] eak and short-lived immune response to current non-adjuvanted trivalent influenza vaccines (TIVs) because their immune systems are immature. The addition of adjuvants to trivalent influenza vaccines (aTIVs) can enhance the immune response, potentially improving protection in this population.The influenza vaccine FLUAD® includes the oil-in-water adjuvant MF59, which has been shown to boost the immu […]


Incorporating structure context of HA protein to improve antigenicity calculation for influenza virus A/H3N2

Sci Rep
PMCID: 4976332
PMID: 27498613
DOI: 10.1038/srep31156

[…] 94 on 120 independent testing set to classify the antigenicity similarity (see ).Further, our model was compared with several online programs on independent testing dataset, including Lee and Chen’s, ATIVS(Liao & Lee), Lees and Shepherd’s and AntigenCO (). In addition to classification accuracy, parameters of Mathew Correlation Coefficient (MCC) and F-score were also introduced to indicate the pot […]


SeqMonitor: Influenza Analysis Pipeline and Visualization

PLoS Curr
PMCID: 2762774
PMID: 20025203
DOI: 10.1371/currents.RRN1040

[…] opment are allowing the quick identification of important, novel mutations using 3-d protein structures , as well as H3N2 antigenic-site-based vaccine prediction systems (  .  This type of automated detection and monitoring of novel mutations affecting antigenicity, convergent evolution, and inter/intra-host reassortment needs to be performed on a conti […]


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ATIVS institution(s)
Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, Taiwan; Vaccine R&D Center, National Health Research Institutes, Taiwan
ATIVS funding source(s)
Supported by Centers for Disease Control, Taiwan (DOH95-DC-1401); National Research Program for Genomic Medicine, National Science Council, Taiwan (NSC95-3112-B-400- 005).

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