AUCpreD statistics

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AUCpreD specifications


Unique identifier OMICS_12717
Name AUCpreD
Interface Web user interface
Restrictions to use None
Input data Protein sequence(s)
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Sheng Wang <>

Publication for AUCpreD

AUCpreD in publications

PMCID: 5869567
PMID: 29610665
DOI: 10.1002/prp2.386

[…] a healthy volunteer (n = 12) study in which participants were administered a single oral dose (5 mg) of midazolam. aucobs, observed area under the plasma concentration‐time curve (nmol/l × hours); aucpred, predicted area under the plasma concentration‐time curve (nmol/l × hours); aucind, predicted area under the plasma concentration‐time curve following rifampin induction (nmol/l × hours); […]

PMCID: 5748442
PMID: 28975382
DOI: 10.1007/s00228-017-2344-x

[…] \begin{document}$$ rmse=\sqrt{\frac{1}{n}{\sum}_i^n{\left(\frac{au{c_{pred}}^{(i)}- au{c_{obs}}^{(i)}}{au{c_{obs}}^{(i)}}\right)}^2}\times 100 $$\end{document}rmse=1n∑in(aucpred(i)−aucobs(i)aucobs(i))2×100 , for each lss, distribution symmetry and range of relative errors was verified []., for the linear regression method, the best strategies were used to predict […]

PMCID: 4860366
PMID: 27162478
DOI: 10.4196/kjpp.2016.20.3.245

[…] demographic data. the predicted and measured concentrations were compared by a visual predictive check (vpc). maximum a posteriori bayesian estimators were estimated to calculate the predicted auc (aucpred). the accuracy and precision of the aucpred values were assessed by calculating the mean prediction error (mpe) and root mean squared prediction error (rmse), and compared with the target auc […]

PMCID: 2039832
PMID: 17712551
DOI: 10.1007/s00228-007-0354-9

[…] curve (auc0–12) was calculated from the time versus tacrolimus concentration plot using the linear trapezoidal rule in mwpharm 3.50 (mediware, groningen, the netherlands). the predicted auc0–12 (aucpred), calculated with the 24 different lss, were validated by determining the predictive performance as described by sheiner and beal []. the percentage of the prediction error (pe) […]

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AUCpreD institution(s)
Toyota Technological Institute at Chicago, Chicago, IL, USA; Department of Human Genetics, University of Chicago, Chicago, IL, USA
AUCpreD funding source(s)
This study was supported by the National Institutes of Health (R01GM0897532) and National Science Foundation (DBI-0960390).

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