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|Interface||Web user interface|
|Restrictions to use||None|
|Input data||Protein sequence(s)|
- person_outline Sheng Wang
Publication for AUCpreD
Population pharmacokinetics of treosulfan and development of a limited sampling strategy in children prior to hematopoietic stem cell transplantation
[…] rror (RMSE). These parameters were estimated using following equations (Eq. –):5PE=AUCpredi−AUCobsiAUCobsi×100 6MPE=1N∑iNAUCpredi−AUCobsiAUCobsi×100 7MAPE=1N∑iNAUCpredi−AUCobsiAUCobsi×100 8RMSE=1N∑iN(AUCpred(i)−AUCobs(i)AUCobs(i))2×100 For each LSS, distribution symmetry and range of relative errors was verified .For the linear regression method, the best strategies were used to predict AUC0 → ∞ […]
Prospective validation of a novel dosing scheme for intravenous busulfan in adult patients undergoing hematopoietic stem cell transplantation
[…] The AUC for the daily busulfan dose was predicted for each patient. This predicted AUC (AUCPRED) was calculated as follows: AUCPRED=Dosei/CLBayesian where Dosei was the individual daily amount of busulfan administered and CLBayesian was the maximum a posteriori Bayesian estimate of clear […]
Evaluation of limited sampling strategies for tacrolimus
[…] tion curve (AUC0–12) was calculated from the time versus tacrolimus concentration plot using the linear trapezoidal rule in MWPharm 3.50 (Mediware, Groningen, The Netherlands). The predicted AUC0–12 (AUCpred), calculated with the 24 different LSS, were validated by determining the predictive performance as described by Sheiner and Beal . The percentage of the prediction error (PE) and the percen […]
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