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AutoEPG specifications


Unique identifier OMICS_33344
Name AutoEPG
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input format ABF,ATF
Operating system Unix/Linux, Windows
Programming languages MATLAB
Computer skills Advanced
Stability Stable
Maintained Yes


No version available


  • person_outline James Dillon

Publication for AutoEPG

AutoEPG citations


An optogenetic arrhythmia model to study catecholaminergic polymorphic ventricular tachycardia mutations

Sci Rep
PMCID: 5727474
PMID: 29235522
DOI: 10.1038/s41598-017-17819-8

[…] uration: 10 ms, over a period of 5 seconds each). Review software (Bruxton Corporation, Seattle, WA, USA) was used to translate PatchMaster files to ABF files. Pump rate and duration were analyzed by AutoEPG (kindly provided by Dr. Christopher James, Embody Biosignals Ltd., UK). Excel was used for calculation of means and SEM, 1-way ANOVA with Bonferroni post-hoc test was performed using OriginPro […]


Microfluidic platform for electrophysiological recordings from host stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research

PMCID: 5196495
PMID: 27751868
DOI: 10.1016/j.ijpddr.2016.08.001

[…] made by transecting C. elegans and sucking the exposed pharynx into a pipette (forming a seal with relatively high electrical resistance and well-defined geometry), the conditions used by for their ‘AutoEPG’ pump-recognition program. To accommodate EPG variability, the algorithm used in the present study compensated for changes in EPG amplitude during the recording and automatically optimized rec […]


Chemical activation of a food deprivation signal extends lifespan

Aging Cell
PMCID: 5013014
PMID: 27220516
DOI: 10.1111/acel.12492

[…] (Hu et al., ). Briefly, the worms were placed in the device in Dent's solution supplemented with 5 mm 5‐HT (to stimulate pumping) and recorded for 2–5 min. Recorded EPG traces were analyzed using the AutoEPG software (Dillon et al., ), which annotates and compiles individual features of the traces such as P spikes. Two‐way ANOVA within GraphPad Prism™ software was used to test significance. […]


Arrhythmogenic effects of mutated L type Ca2+ channels on an optogenetically paced muscular pump in Caenorhabditis elegans

Sci Rep
PMCID: 4585839
PMID: 26399900
DOI: 10.1038/srep14427

[…] in a concentration of 10 μM. Final DMSO concentration was ~0.1%.We used Review software (Bruxton Corporation, USA) to translate PatchMaster files to ABF files. Pump rate and duration were analyzed by AutoEPG (kindly provided by C. James, Southampton, UK). Excel was used for calculation of means and s.e.m., 1-way ANOVA with Fisher post-hoc test was performed using OriginPro (OriginLab, USA). […]


NeuroChip: A Microfluidic Electrophysiological Device for Genetic and Chemical Biology Screening of Caenorhabditis elegans Adult and Larvae

PLoS One
PMCID: 3661448
PMID: 23717588
DOI: 10.1371/journal.pone.0064297

[…] ngs were made for 5 minutes for the comparison of EPG parameters between conventional and chip recordings, and for 2 minutes for the screening experiments. They were analysed either manually or using AutoEPG , as indicated. The EPG parameters that were measured were i) peak to peak amplitude (manually) ii) average frequency (AutoEPG) iii) the duration of a single EPG waveform or ‘pump’ measured as […]


AutoEPG: Software for the Analysis of Electrical Activity in the Microcircuit Underpinning Feeding Behaviour of Caenorhabditis elegans

PLoS One
PMCID: 2795780
PMID: 20041123
DOI: 10.1371/journal.pone.0008482

[…] The AutoEPG graphical user interface (GUI) is composed of two windows, the annotation and navigation windows (), which have different capabilities. When an EPG trace is first opened in AutoEPG the entire […]


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AutoEPG institution(s)
School of Biological Sciences, Bassett Crescent East, University of Southampton, Southampton, UK; Signal Processing and Control Group, Institute of Sound and Vibration Research, University of Southampton, Southampton, UK; School of Psychology, University of Southampton, Southampton, UK
AutoEPG funding source(s)
Supported by the BBSRC as part of a ‘cross-council MRC/BBSRC initiative in mental health.’ Grant Number BB/ E022251/1.

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