B-cell epitope databases | Immunology system data analysis
B-cell epitopes (or, antibody epitopes) can be defined as regions on molecules that are specifically bound by B-cell receptors (antibodies). They can include native protein structures, linear peptides, carbohydrates and other biological macromolecules. The majority of short linear peptides have the potential to be B-cell epitopes.
Compiles experimental data dealing with antibody and T-cell epitopes studied in various animal species encompassing humans and non-human primates. IEDB proposes a repository allowing six types of searches, including queries by assay, host or epitope, coupled to utilities for t- or b-cell epitope prediction. Data available on this database is derived from various diseases such as allergic or infectious ones as well as from diseases associated with transplantation.
Helps students and researchers to understand all aspects of biomedicine and agriculture, from protein synthesis to health and disease. RCSB PDB is a database that provides a resource powered by the Protein Data Bank (PDB) archive - information about the 3D shapes of proteins, nucleic acids, and complex assemblies. Users can perform simple and complex queries on the data, analyze, and visualize the results.
Provides access to well-documented and tested epitope-related tools through a common style of web interface. IEDB-AR is a database that allows users to easily make direct comparisons between and among various prediction methods. The IEDB-AR provides five analytical tools for: (i) calculating the epitope population coverage; (ii) assessing the degree of conservancy of an epitope; (iii) visualization and analysis of 3D structures of molecules containing epitopes; (iv) clustering of epitope sequences and (v) mapping of epitopes onto 3D protein structures.
A database of all known antigenic residues and the antibodies that interact with them, including a detailed description of residues involved in the interaction and their sequence/structure environments.
A collection of immunogenic peptides.The database is consist of nearly 555 antigenic peptide with varying immunogenic activity. The each entry of the database provide complete information about the antigenic peptide.
An open database listing known adverse drug reactions with Human leukocyte antigens (HLA) alleles. The HLA-ADR has been implemented within the wider Allele Frequency Net Database (AFND), which stores large collections of data on the allele and haplotype frequencies for healthy, worldwide populations, as well as modules for exploring immunogenetic disease associations. HLA-ADR provides a resource that not only facilitates meta-analyses but also enables users to further their investigations by using resources available with the main AFND website, e.g. on the incidence of particular HLA alleles/haplotypes in healthy worldwide populations.
A special database of well-defined conformational epitopes. CED provides a collection of conformational epitopes and related information including the residue make up and location of the epitope, the immunological property of the epitope, the source antigen and corresponding antibody of the epitope. All entries in this database are manually curated from articles published in peer review journals.
A database of cereal prolamin epitopes, peptides and proteins for expert users that are dealing with protein chemistry, proteomics and mass spectrometry, method developments and related applications in food science, agricultural breeding or medical studies. ProPepper™ contains the full scale of currently available prolamin sequences and specific in silico digested peptide entries, links to reference databases (Uniprot, NCBI & IEDB) and cross-referenced connections. The interface allows advanced global and parametric search functions along with a download option, with direct connections to the relevant public databases.
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