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Sequence-based B-cell epitope detection software tools | Immune system data analysis

Sequence-based B-cell epitope detection software tools | Immune system data analysis For over 30 years, computational methods have been developed for facilitating epitope recognition. In the past, the majority of the in silico methods were focused on linear epitopes. Most of these approaches are sequence-based and use amino acid-based propensity scales, such as hydrophilicity, solvent accessibility, secondary structure and flexibility; a score derived from the propensity scales is assigned to each residue, and the whole sequence is examined for high-scoring window fragments, which are then predicted as epitopes.
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