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Sequence-based B-cell epitope detection software tools | Immunoinformatics

For over 30 years, computational methods have been developed for facilitating epitope recognition (El-Manzalawy and Honavar, 2010). In the past, the majority of the in silico methods were focused on linear epitopes. Most of these approaches are…
ABCpred
Desktop
Web

ABCpred

Predicts B cell epitope(s) in an antigen sequence, using artificial neural…

Predicts B cell epitope(s) in an antigen sequence, using artificial neural network. ABCpred is able to predict epitopes with 65.93% accuracy using recurrent neural network.

Bayesb
Web

Bayesb

Provides users a support vector machines (SVM) prediction model using Bayes…

Provides users a support vector machines (SVM) prediction model using Bayes Feature Extraction (BFE) to predict linear B-cell epitopes of diverse lengths (12- to 20-mers). Bayesb is based on the…

SEPIa
Desktop

SEPIa

Uses a voting algorithm for combining the predictions of two classifiers, a…

Uses a voting algorithm for combining the predictions of two classifiers, a Gaussian Naïve Bayes and a Random Forest classifier. SEPIa is a conformational epitope prediction method that requires…

BEST
Desktop

BEST Bcell Epitope prediction using Support vector machine Tool

Predicts epitopes from full protein chains using an approach based on averaging…

Predicts epitopes from full protein chains using an approach based on averaging selected scores generated from 20-mers by a support vector machine (SVM)-based predictor. BEST uses a sliding window to…

EpIC
Web

EpIC a rational pipeline for Epitope Immunogenicity Characterization

Allows the user to easily, quickly, and accurately increase the immunogenicity…

Allows the user to easily, quickly, and accurately increase the immunogenicity of peptide epitopes through selective inclusion of endogenous B-cell epitopes that exist within the target protein…

PEASE
Web

PEASE Predicting Epitopes using Antibody SEquence

A web-server predicting antibody-specific epitopes, utilizing the sequence of…

A web-server predicting antibody-specific epitopes, utilizing the sequence of the antibody. The predictions are provided both at the residue level and as patches on the antigen structure. The…

Bcell-HCV
Web

Bcell-HCV

Determines linear B-cell epitopes in hepatitis C virus (HCV). Bcell-HCV is a…

Determines linear B-cell epitopes in hepatitis C virus (HCV). Bcell-HCV is a web server that can deal with the amino acid sequences of HCV antigens. It returns the identified B-cell epitopes with…

LBEEP
Desktop

LBEEP Linear B-Cell Exact Epitope Predictor

A perl based open source tool for the prediction of Linear B-cell epitopes. The…

A perl based open source tool for the prediction of Linear B-cell epitopes. The proposed method is made as a stand-alone tool available freely for researchers, particularly for those interested in…

EpiPred
Desktop

EpiPred Epitope Prediction

A method to identify the epitope region on the antigen, given the structures of…

A method to identify the epitope region on the antigen, given the structures of the antibody and the antigen. EpiPred combines conformational matching of the antibody-antigen structures and a…

bcRep
Desktop

bcRep B cell receptor repertoire

Methods for advanced analysis of B cell receptor repertoire data, like gene…

Methods for advanced analysis of B cell receptor repertoire data, like gene usage, mutations, clones, diversity, distance measures and multidimensional scaling and their visualisation.

EPMLR
Web

EPMLR

A web-server which enables users to predict Linear B-cell epitope with their…

A web-server which enables users to predict Linear B-cell epitope with their interested protein or peptide. Users just need to paste or type protein sequence into the box of the Prediction page.…

BCPREDS
Web

BCPREDS

The identification and characterization of B-cell epitopes play an important…

The identification and characterization of B-cell epitopes play an important role in vaccine design, immunodiagnostic tests, and antibody production. BCPREDS is a method for predicting linear B-cell…

LBtope
Desktop
Web

LBtope

One of the major challenges in designing a peptide-based vaccine is the…

One of the major challenges in designing a peptide-based vaccine is the identification of antigenic regions in an antigen that can stimulate B-cell's response, also called B-cell epitopes.…

SVMTriP
Web

SVMTriP

A method to predict antigenic epitope with lastest sequence input from IEDB…

A method to predict antigenic epitope with lastest sequence input from IEDB database. Support Vector Machine (SVM) has been utilized by combining the Tri-peptide similarity and Propensity scores…

IgPred
Desktop
Web

IgPred

A web server developed for predicting different types of B-cell epitopes that…

A web server developed for predicting different types of B-cell epitopes that can induce different class of Antibodies like IgG, IgE and IgA. In past large number of methods have been developed for…

BepiPred
Web

BepiPred

Predicts the location of linear B-cell epitopes using a combination of a hidden…

Predicts the location of linear B-cell epitopes using a combination of a hidden Markov model (HMM) and a propensity scale method. BepiPred is a web server constructed from a large set of structurally…

BEOracle
Desktop

BEOracle B-Cell Epitope Oracle

Provides support vector machine (SVM) classifier models. The BROracle…

Provides support vector machine (SVM) classifier models. The BROracle classifier utilizes BEOracle scores as features and therefore predicts using the information from local features only. The…

COBEpro
Web

COBEpro

A two-step system for predicting continuous B-cell epitopes. COBEpro is…

A two-step system for predicting continuous B-cell epitopes. COBEpro is incorporated into the SCRATCH prediction suite.

CBTOPE
Web

CBTOPE

One of the major challenges in the field of vaccine design is to predict…

One of the major challenges in the field of vaccine design is to predict conformational B-cell epitopes in an antigen. CBTOPE has been developed for predicting B-cell epitope.

Bcepred
Desktop
Web

Bcepred

Prediction of linear B-cell epitopes, using physico-chemical properties.…

Prediction of linear B-cell epitopes, using physico-chemical properties. Bcepred is able to predict epitopes with 58.7% accuracy using Flexibility, Hydrophobicity, Polarity, and Surface properties…

APCpred
Web

APCpred

A model for prediction of linear B-cell epitopes which was derived from the…

A model for prediction of linear B-cell epitopes which was derived from the combination of amino acid anchoring pair composition (APC) and Support Vector Machine (SVM) methods. Systematic comparisons…

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