Computational protocol: Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers

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Protocol publication

[…] All data for UVRAG frameshift mutation in human CRC, gastric, and endometrial cancers with MSI were obtained from SelTarbase (http://www.seltarbase.org/) and primary public sources. All data for DNA sequence alteration, chromosomal structure variants, and clinical information in gastric cancer were obtained from cBioportal (http://www.cbioportal.org) and primary sources. All statistical analyses were carried out using the R software package. Circos plots were carried out using Circos (http://circos.ca/). […]

Pipeline specifications

Software tools cBioPortal, Circos
Databases SelTarbase
Application Genome data visualization
Organisms Homo sapiens
Diseases Neoplasms, Colorectal Neoplasms