Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 6
Release date: Sep 8 2017
Last update date: Nov 24 2017
Access: Public
Diseases: Neoplasms
Chemicals: Sirolimus
Dataset link A UBE2O-AMPKα2 axis that promotes tumor initiation and progression offers opportunities for therapy

Experimental Protocol


In order to elucidate the pathophysiological impact of UBE2O loss, we generated mouse embryonic fibroblasts (MEFs), derived from day 13.5 embryos of C57BL6 mice, stably expressing control or Ube2o shRNA. We then performed microarray analysis in these cells. Three independent MEFs from each shRNA were analyzed. Gene expression profile analysis in these cells will reveal target genes and pathways differentially regulated upon UBE2O-loss.

Repositories


GEO

GSE92919

BioProject

PRJNA358834

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Contact


Min Sup Song