Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 7
Release date: Dec 9 2010
Last update date: Mar 23 2012
Access: Public
Diseases: Dental Caries
Dataset link Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation (expression)

Experimental Protocol


In order to identify alternative splicing events influenced by changes in pol II elongation, we performed quantitative alternative splicing microarray profiling (Pan et al., 2004 (PMID 15610736); Shai et al., 2006 (PMID 16403798)) of RNA isolated from stimulated Jurkat T lymphoma cells, cultured separately in the presence or absence of two different drugs that can inhibit pol II elongation: 5,6-dichloro-1-β-D-ribofuranosyl-benzimidazole (DRB) and camptothecin.

Repositories


GEO

GSE25287

ArrayExpress

E-GEOD-25287

BioProject

PRJNA142561

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Contact


Qun Pan