|Application:||Gene expression microarray analysis|
|Number of samples:||7|
|Release date:||Dec 9 2010|
|Last update date:||Mar 23 2012|
|Dataset link||Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation (expression)|
In order to identify alternative splicing events influenced by changes in pol II elongation, we performed quantitative alternative splicing microarray profiling (Pan et al., 2004 (PMID 15610736); Shai et al., 2006 (PMID 16403798)) of RNA isolated from stimulated Jurkat T lymphoma cells, cultured separately in the presence or absence of two different drugs that can inhibit pol II elongation: 5,6-dichloro-1-β-D-ribofuranosyl-benzimidazole (DRB) and camptothecin.