|Number of samples:||4|
|Release date:||Nov 21 2018|
|Last update date:||Nov 30 2018|
|Genes:||IL2, FOXP3, CD4, PPA1, ERRa|
|Dataset link||Role of interleukin 2 on chromatin landscapes in lymph node Foxp3+ CD4+ regulatory (Treg) cells|
LNs from 6-8 weeks old aged-matched females either Il2ramut/mut (2 mice) or WT (2 mice) Foxp3-RFP+ reporter mice were harvested and RFP+ Treg cells were enriched by negative selection (dynabeads) and flow-sorted (Aria III) before proceeding to extraction of nuclei, transposition and library preparation for sequencing (ATAC-seq).