Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 30
Release date: Aug 10 2010
Last update date: Aug 20 2013
Access: Public
Diseases: Cardiovascular Diseases, Diabetes Mellitus, Type 2, Metabolic Diseases
Dataset link A high fat diet causes obesity and insulin resistance in mice, but induces small changes in the muscle transcriptome

Experimental Protocol


In this study, C57BL/6J mice were fed a high fat (HF) diet for 8 weeks to induce obesity and insulin resistance. Plasma levels of the adipokines leptin and adiponectin were measured. To investigate how these metabolic disturbances will influence the skeletal muscle transcriptome we performed whole-genome microarray analysis. Functional implications were assessed by analyses of predefined gene sets based on Gene Ontology, biochemical, metabolic and signaling pathways.

Repositories


GEO

GSE17576

ArrayExpress

E-GEOD-17576

BioProject

PRJNA118525

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Contact


Janneke de Wilde