Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 6
Release date: Feb 16 2018
Last update date: Nov 30 2018
Access: Public
Diseases: Heart Failure, Cardiomyopathies, Acute Kidney Injury
Chemicals: Creatinine
Dataset link Increased Susceptibility to AKI in a Mouse Model of Presymptomatic Cardiomyopathy

Experimental Protocol


mRNA profiles were generated by performing RNA-seq on adult kidney tissue from transgenic mice (FVB/N mice that overexpress CryAB containing the R120G missense mutation driven by the cardiomyocyte-specific α-myosin heavy chain promoter. We performed analysis in triplicate of kidneys from transgenic animals (prior to the onset of heart failure) vs. age-matched, sex-matched (male) control mice by deep sequencing using Illumina Hi-Seq 2500.

Repositories


GEO

GSE99703

ENA

SRP108641

BioProject

PRJNA389324

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Contact


Keri Drake