Computational protocol: Comparative Genomic Hybridization Identifies Virulence Differences in Streptococcus suis

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Protocol publication

[…] All mobile genes were excluded from the analysis. The absence or presence of a gene was converted into a binary code (gene present in a given strain = 1, absent or highly divergent = 0) and analyzed using Cluster/TreeView. Trees based on the un-weighted-pair group method using average linkages (UPGMA) were constructed with BioNumerics (version 3.0; Applied Maths BVBA, Belgium). The correlations between these trees were calculated with BioNumerics. […]

Pipeline specifications

Software tools TreeViewX, BioNumerics
Application Phylogenetics
Organisms Streptococcus suis
Diseases Encephalitis, Arbovirus