Dataset features

Specifications


Application: BS-seq analysis
Number of samples: 11
Release date: Jun 14 2018
Last update date: Nov 1 2018
Access: Public
Diseases: Breast Neoplasms, Neoplasms
Chemicals: Amino Acids
Dataset link Paternal malnutrition programs offspring’s breast cancer risk and tumor metabolism in a mouse model (MBD-seq)

Experimental Protocol


Male mice were fed AIN93G-based diets containing either 17.7% (control) or 8.9% (LP) energy from protein from 3 to 10 weeks of age. Males on either group were mated to females raised on a control diet. Female offspring control and LP fathers were treated with 7,12-dimethylbenz[a]anthracene (DMBA) to initiate mammary carcinogenesis. Mature sperm from fathers and mammary tissue from female offspring were used for DNA methylation analyses.

Repositories


GEO

GSE114422

ENA

SRP145631

BioProject

PRJNA471326

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Contact


Lu Jin