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Babel | Assessing gene-level translational control from ribosome profiling

An analytical methodology for assessing the significance of changes in translational regulation within cells and between conditions. This approach facilitates the analysis of translation genome-wide while allowing statistically principled gene-level inference. Babel is based on an errors-in-variables regression model that uses the negative binomial distribution and draws inference using a parametric bootstrap approach.

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Babel forum

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Babel classification

Babel specifications

Unique identifier:
OMICS_01530
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU Lesser General Public License version 3.0
Version:
0.2-6
Requirements:
edgeR
Software type:
Framework/Library
Restrictions to use:
None
Programming languages:
R
Computer skills:
Advanced
Stability:
Stable
Maintained:
Yes

Babel distribution

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No versioning.

Babel support

Documentation

Maintainer

  • Adam B. Olshen <>

Credits

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Publications

Institution(s)

Department of Epidemiology and Biostatistics, Helen Diller Family Comprehensive Cancer Center, Department of Medicine and Department of Urology, University of California, San Francisco, CA, USA; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, USA

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