BACH specifications

Information


Unique identifier OMICS_11389
Name BACH
Alternative name Bayesian 3D constructor for Hi-C data
Software type Package/Module
Interface Command line interface, Graphical user interface
Restrictions to use None
Input data BACH takes the Hi-C contact matrix and local genomic features (restriction enzyme cutting frequencies, GC content and sequence uniqueness) as input.
Output data BACH produces, via MCMC computation, the posterior distribution of three-dimensional (3D) chromosomal structure.
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Stability Stable
Requirements GNU scientific
Maintained Yes

Versioning


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Maintainer


  • person_outline Ming Hu <>

Publication for Bayesian 3D constructor for Hi-C data

BACH institution(s)
Department of Statistics, Harvard University, Cambridge, MA, USA; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA; Ludwig Institute for Cancer Research, La Jolla, CA, USA; Medical Scientist Training Program, University of California, San Diego, La Jolla, CA, USA; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA, USA; Bioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, CA, USA; University of California, San Diego School of Medicine, Department of Cellular and Molecular Medicine, Institute of Genomic Medicine, UCSD Moores Cancer Center, La Jolla, CA, USA
BACH funding source(s)
This work was supported by the Ludwig Institute for Cancer Research, US National Institutes of Health grants R01HG005119, R01HG003991 and 5R01GM080625.

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