Allows users to align large numbers of next generation DNA sequences. BarraCUDA uses the Burrows-Wheeler algorithm. This software aligns short noisy DNA sequences against one of the increasing number of reference genomes. It can align human DNA sequences when run on nVidia consumer Graphics processing unit (GPU) cards with more than 4 GB of memory, e.g. the GeForce GT 730. The software was built with default setting and a second version was built specifically for the GT 730.