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BASC specifications


Unique identifier OMICS_03287
Restrictions to use None
Maintained Yes


  • person_outline David Edwards

Publication for BASC

BASC citations


Automated cell type classification in intact tissues by single cell molecular profiling

PMCID: 5802843
PMID: 29319504
DOI: 10.7554/eLife.30510.019

[…] es in re-colored t-SNE plots (). We found a small cloud of cells between the Club and AT2 clusters that expressed both Sftpc and Scgb1a1. On the basis of this dual expression, we assigned them as the BASC type (). We also noted that Lyz2 expression partitioned the AT2 cells into two classes designated Lyz2+ and Lyz2-, while Actb segregated Club cells into two classes designated ActbHi and ActbLo. […]


Stability of Signaling Pathways during Aging—A Boolean Network Approach

PMCID: 5745451
PMID: 29258225
DOI: 10.3390/biology6040046
call_split See protocol

[…] GG database (95 genes; []). 86 of these 95 genes could be found in the aforementioned human gene expression dataset. The gene expression values of these 86 genes were selected and binarized using the BASC A algorithm [,]. Binarization was done using the same threshold for all samples. To reduce the size of the Boolean networks all genes that were significantly binarizable (p < 0.05) according to B […]


Everolimus for treatment of tuberous sclerosis complex‐associated neuropsychiatric disorders

PMCID: 5740257
PMID: 29296616
DOI: 10.1002/acn3.494

[…] grooved pegboard. Parent rating scales included the Vineland Adaptive Behavioral Scales‐II (VABS2); Behavior Rating Inventory of Executive Function (BRIEF), Behavior Assessment System for Children 2 (BASC2), Strengths and Difficulties Questionnaire (SDQ), and Social Responsiveness Scale (SRS). Academic skills were measured by Reading and Math subtests of the Wide Range Achievement Test‐4 (WRAT4). […]


Pattern of Reduced Functional Connectivity and Structural Abnormalities in Parkinson’s Disease: An Exploratory Study

PMCID: 5233672
PMID: 28133455
DOI: 10.3389/fneur.2016.00243

[…] nctional networks in data randomly generated, since the algorithm used is an optimization procedure, and values can vary due to the chosen threshold and variability among patients (). Conversely, the BASC method provides a fully automated alternative that applies to an arbitrarily large number of networks (). BASC renders more robust results since it uses the growth region to find networks and obs […]


Quality of life, psychological adjustment, and adaptive functioning of patients with intoxication type inborn errors of metabolism – a systematic review

Orphanet J Rare Dis
PMCID: 4219016
PMID: 25344299
DOI: 10.1186/s13023-014-0159-8

[…] scoring of the IT-IEM group than of norms. Higher scorings are favourable for all scales, except for two cases: the Child Behaviour Checklist (CBCL) and the Behaviour Assessment System for Children (BASC) (all subscales but adaptive skills) report problem behaviour. Consequently, higher scores signify more problems and are unfavourable outcomes. For dichotomous outcomes, we used Chi-square tests, […]


Helicase Like Transcription Factor (Hltf) Regulates G2/M Transition, Wt1/Gata4/Hif 1a Cardiac Transcription Networks, and Collagen Biogenesis

PLoS One
PMCID: 3835564
PMID: 24278285
DOI: 10.1371/journal.pone.0080461

[…] ose protein product is a critical component of the microtubule organizing center (MTOC), as well as downregulation of the Brca1gene and 12 members of the Brca1 associated genome surveillance complex (BASC) in DNA damage repair (). This collective loss of gene expression is expected to compromise DNA double-strand break repair, trigger pro-apoptosis signaling, and cause heart dysfunction.The morpho […]


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BASC institution(s)
Plant Biotechnology Centre, Victorian AgriBiosciences Centre, Victoria, Australia

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